ICD-10-CM Book 2025 Edition
Chapters ICD-10-CM Book Table of Content /
chapter 18 R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified /
R50-R69 General symptoms and signs /
R65 Symptoms and signs specifically associated with systemic inflammation and infection
Billable ICD-10-CM Code R65.11
R65.11
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Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction 
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useAdditionalCode
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code to identify specific acute organ dysfunction, such as: |
acute kidney failure (N17.-) |
acute respiratory failure (J96.0-) |
critical illness myopathy (G72.81) |
critical illness polyneuropathy (G62.81) |
disseminated intravascular coagulopathy [DIC] (D65) |
encephalopathy (metabolic) (septic) (G93.41) |
hepatic failure (K72.0-) |
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